Chromo- and fluorophoric water-soluble polymers and silica particles by nucleophilic substitution reaction of poly(vinyl amine)

• Katja Hofmann,
• Ingolf Kahle,
• Frank Simon and
• Stefan Spange

Beilstein J. Org. Chem. 2010, 6, No. 79, doi:10.3762/bjoc.6.79

• chromophoric and fluorescent carbonitrile-functionalized poly(vinyl amine) (PVAm) and PVAm/silica particles were synthesized by means of nucleophilic aromatic substitution of 8-oxo-8H-acenaphtho[1,2-b]pyrrol-9-carbonitrile (1) with PVAm in water. The water solubility of 1 has been mediated by 2,6-O-β

• ; poly(vinyl amine); Introduction Fluorescent polymers are an important tool for the study of molecular dynamics and also find use as sensor probes for biologically active compounds [1]. In recent years, there has been great interest in the synthesis, characterization and applications of fluorescent

• concerning its synthesis and purification. An alternative pathway is the chemical modification of commercially available polymers containing reactive groups which can react with fluorescent dyes [6]. Poly(vinyl amine)s (PVAm) are copolymers made by the hydrolysis of poly(vinyl formamide) (PVFA). Fully